Linda,
I sent you a PM with the step-by-steps on how this can be done in SmarterMail. We had the same problem when we migrated 10 large domains with several thousand users over from IMail, as many of those customers were elderly and not technically savvy enough to reconfigure their mail clients with their full email address and frankly our Customer Support department was already going to be overwhelmed with calls for webmail support as it was. So, to make the migration smoother we assigned a unique IP to each domain and bound the unique IP and unique hostname in IIS & Smartermail and it worked a charm.
Let me know if you need any specific guidance. There is some web.config wizardry I can share too that can help if you were using IMail on the old default port of 3000.