You should be able to do that, just make sure ports aren't used by anything else and in SM you can use "localhost:<rspam port>" to connect to it.
Keep in mind we'll also run clamav on linux (ubuntu via apt-get), clamav uses about a gig of RAM with some spiking when it updates.
Matt Petty
Senior Software Developer
SmarterTools Inc.
www.smartertools.com