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Are you planning on creating a mobile client? We are currently using Outlook, but we would be willing to drop it in favor of a native SmarterMail mobile client that supports all features (mail, calendar, contacts, chat, meeting).
In the current form, we cannot use chat because the message delivery is limited to the web client or, I assume, a separate XMPP client.
An all-in-one mobile client would basically pull all available features together and provide the user with a universal messaging client.