Hi Parinda, I'm sorry to hear you're having issues with corruption and I'd like to see if I can help narrow down the source. First, I recommend downloading Process Monitor from Sysinternals/Microsoft and configuring it with these filters:
IF PROCESS = MAILSERVICE.EXE THEN EXCLUDE
IF PROCESS = W3WP.EXE THEN EXCLUDE
IF PROCESS = EXPLORER.EXE THEN EXCLUDE
IF PATH CONTAINS C:\SMARTERMAIL\Domains (Adjust for your environment) THEN INCLUDE
Once those are in place hit Filter>Drop Filtered Events and let it run for a bit. Anything that shows up in that list at that point would be another application touching the files inside of user directories, and is likely the source of corruption. If you don't see anything else noted here please note that on your ticket as development will want to check that. I hope that helps!
Kyle Kerst
Acting IT Manager
SmarterTools Inc.
www.smartertools.com