Hello Andy. Do you have any error logs being generated by SmarterStats in and around the time you last tried to log on? Those logs can be found in:
C:\Program Files (x86)\SmarterTools\SmarterStats\MRS\App_Data\Logs
Also, if you log on as the system administrator can you impersonate the site from there, or does this fail as well?
Kyle Kerst
IT Coordinator
SmarterTools Inc.
www.smartertools.com