I believe the only person that could initiate an invite being sent/an updated invite being sent would be the organizer or someone who has edit permissions to the event like someone who has full control over that calendar and its associated appointments. So, this would make me suspicious of the original organizer's email client as a potential culprit. I see you submitted a ticket and Tony is taking a look, so you should be in good hands.
In the meantime though I went ahead and submitted a feature request to have more details logged either under a standard log category or via debug logging that will track appointment details, sender/attendee info, client and protocol information, etc. Hopefully this will come in handy in the future!
Kyle Kerst
IT Coordinator
SmarterTools Inc.
www.smartertools.com