Hello Jarod. I don't believe the temp file location used can be modified, as this path is picked up from the .NET platform and isn't something configured in SmarterMail. Out of curiosity; what is filling up your temp directory? In the meantime, I'd recommend implementing a cleanup routine for that directory which should help keep things moving forward!
Kyle Kerst
IT Coordinator
SmarterTools Inc.
www.smartertools.com