Hi Steve.  I've run across quite a few cloud installs running on Amazon's AWS service with no issues related to the environment.  The biggest thing I've heard to watch out for is to make sure IP addresses don't get rotated, which some services do.

Hi Steve,

 

We are a SmarterTools authorized Lease-Reseller and can offer you a complete cloud-based solution for SmarterMail. We take care of all the setup and configuration of the server and software. Also, we install updates, perform general maintenance, and monitor 24x7 so your email service is worry-free. You get an admin account to manage users, free tech support, and a single monthly invoice. If interested, click on my name above to start a private conversation.

 

Thanks!

Kevin