Yes, it is. BUT you have to use the manual installer instead of the automated one and set up separate IIS sites for each one. In addition, they need to be connected to separate databases. See this article for more help: http://portal.smartertools.com/kb/a2835/set-up-smartertrack-as-an-iis-site-in-iis-8.aspx
Grady Werner
SmarterTools Inc.
www.smartertools.com