In Brian's case I ended up finding out the installer was failing to download pre-requisites (the ARR router and URL Rewrite components) and so while the install was ultimately successful, the necessary prerequisites were missing and so SmarterMail failed to present as you'd expect. The only signs that this was happening were 1) an error being displayed during the installer process and 2) the missing prerequisites per the readme in our installer and so it did take a little bit of poking around to confirm that was what was happening. I'm digging into why Brian's environment is having issues reaching those pieces and will be discussing measures to prevent this in the future with development.
Kyle Kerst
System/Network Administrator
SmarterTools Inc.
(877) 357-6278
www.smartertools.com