No. Non-delivery processing is the same, whether the destination is an MX or an A name. This is per the RFC.
One of the limitations of SmarterMail is that you have poor visibility to the message logs, both incoming and outgoing. That problem can be solved by building your own web solution or by buying a commercial product with a good message review interface, including both delivered and pending messages.
We use a Barracuda appliance as a component of our incoming gateway sequence, It is also the only outbound gateway. It does a decent job of content filtering. For what I wanted, Barracuda is very weak on sender filtering, so we built a front-end gateway using SmarterMail Free, Declude, Python, and SQL
Barracuda has a specific web page for messages that are stuck and awaiting retry. Once you see a stuck message, you can bounce the message and notify the user about their spelling error.
Barracuda also provides a secure web relay solution for sensitive outbound messages. We want all outbound messages to go encrypted, so we set Barracuda to require outbound encryption, then catch the problems and force those destination domains through the secure web relay.
I'm not sure how much life remain in the appliance gateway market, because Barracuda is moving to the cloud like everyone else. Their appliance is capacity-priced, which works very well for us. Their cloud solution is price per-user, which works out to a lot more money for us. I think the appliance pricing will be within the budget of email hosting services on this forum, but I only see the annual maintenance fees, since I have not bought one for cash in more than 15 years. (We use their option for system maintenance includes a new box every 4 years, to avoid obsolescence or repurchase.)