Why not support "Antimalware Scan Interface (AMSI)"
From what I know it is a protocol supported by many antiviruses and perhaps it could be integrated with SmarterMail...
Gabriele Maoret - Head of SysAdmins at SERSIS
Currently manages 6 SmarterMail installations (1 in the cloud for SERSIS which provides services to a few hundred third-party email domains + 5 on-premise for customers who prefer to have their mail server in-house)