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One of the things that I originally thought was confusing, and has now been confirmed as confusing by several of my users, is that certain pages with large buttons at the top of the page (like the Spool page in the Admin -> Manage area, and the Accounts page in the User -> Domain Settings -> Accounts page) are not obvious enough that they are clickable.
We've had several people ask us where they manage their aliases, which is evidence of this. I'm not suggesting to get rid of the buttons as navigation, however, it might be beneficial to add the sub-pages in the left-hand navigation. Something like:
--Waiting To Deliver
I realize that may not be easy since none of those 2nd-level pages have their own URLs and are instead just tabs on the page. But the way they are now just doesn't seem to be obvious enough to most people, as much as I like the "live tile" type of approach. Particularly the Domain Settings -> Accounts page - the buttons at the top aren't obvious to be clickable.
Thanks for the consideration.