Hi Jim. Once you've moved your Domains folder to a new drive, you would simply need to do the following:
- Stop the SmarterMail service.
- Edit the C:\Program Files (x86)\SmarterTools\SmarterMail\Service\domainList.xml file.
- Change all of the "directory=" values to the new location of your SmarterMail domains.
- Restart the SmarterMail service.
I hope this helps.