I wonder if these tips are still valid.
Disable Windows Indexing as this reduces overall disk i/o and extends SSD life
Make sure write caching is enabled
Disable defrag for your spool, especially if you're using a SSD
Defrag RAID arrays at least every couple of days, but do it off hours if possible
Do NOT use a realtime defragger - only use the one within Windows itself
Don't defrag while backing up your mail server